• Doxycycline belongs to the group of tetracyclines and acts bacteriostatic against many Gram-positive and Gram-negative bacteria, like Bordetella, Campylobacter, E. coli, Haemophilus, Pasteurella, Salmonella, Staphylococcus and Streptococcus spp.
• Doxycycline is also active against Chlamydia, Mycoplasma and Rickettsia spp.
• The action of doxycycline is based on inhibition of bacterial protein synthesis.
• Doxycycline has a great affinity to the lungs and is therefore especially useful for treatment of bacterial respiratory infections.
Indications:
• Gastrointestinal and respiratory infections caused by doxycycline sensitive micro-organisms, like Bordetella, Campylobacter, Chlamydia, E. coli, Haemophilus, Mycoplasma, Pasteurella, Rickettsia, Salmonella, Staphylococcus and Streptococcus spp. in calves, goats, poultry, sheep and swine.
Contra Indications:
• Hypersensitivity to tetracyclines.
• Administration to animals of a seriously impaired hepatic function.
• Concurrent administration with penicillins, cephalosporins, quinolones and cycloserine.
• Administration to animals with an active microbial digestion.
Side Effects:
• Discoloration of teeth in young animals may occur.
• Hypersensitivity reactions may occur.
Dosage:
For oral administration:
Calves, goats and sheep:
• Twice daily 1 g per 100 kg body weight for 3 - 5 days.
Poultry and swine:
• 100 g per 500 - 1000 litres of drinking water for 3 - 5 days.
• Note: For pre-ruminant calves, lambs and kids only.
Withdrawal Times:
• Calves, goats and sheep : 14 days.
• Swine : 8 days.
• Poultry : 7 days.
• Not for use in animals from which milk or eggs are produced for human consumption.
